PEPTIDES4ALL Cerebrolysin – Neurotrophic Peptide Mixture for Neuroprotection & Cognitive Research

PEPTIDES4ALL Cerebrolysin is a pharmacologically active peptide and amino acid complex derived from enzymatic hydrolysis of porcine brain proteins.
This low-molecular-weight neurotrophic mixture is designed to mimic the activity of endogenous neurotrophic factors, supporting neuronal survival, synaptic repair, and neuroplasticity.
Because of its multi-modal mechanism, Cerebrolysin has been extensively investigated in models of ischemic stroke, traumatic brain injury (TBI), Alzheimer’s disease, vascular dementia, and neurodegeneration, making it one of the most studied neuroprotective compounds in peptide research.

At the cellular level, Cerebrolysin acts as a broad-spectrum neuropeptide modulator, influencing several overlapping pathways that govern neuronal growth, inflammation, oxidative stress, and apoptosis.
Unlike single-target agents, it provides a multi-target approach to neuroprotection, mimicking the synergistic effects of natural growth factors such as BDNF (brain-derived neurotrophic factor) and GDNF (glial cell line-derived neurotrophic factor) (Frontiers in Neurology, 2023).
Its components cross the blood–brain barrier and interact with neuronal and glial cell populations, enhancing synaptic transmission, mitochondrial function, and neurite outgrowth, while simultaneously reducing oxidative damage and excitotoxicity (Lippincott Journals – Stroke, 2021).

Scientific Evidence & Research Findings

• Enhanced Stroke Recovery – In randomized trials, patients receiving Cerebrolysin showed improved motor and functional outcomes after ischemic stroke, with benefits most evident in early recovery phases. American Heart Association Journals+2PMC+2

• Neuroprotection & Reduced Neuronal Death – In animal models of brain injury and seizures, Cerebrolysin reduced neuronal apoptosis, preserved hippocampal neurons, and increased BDNF expression. Frontiers+1

• Cognitive & Dementia Effects – In Alzheimer’s and vascular dementia trials, Cerebrolysin has been reported to improve cognition, daily functioning, and neuropsychiatric symptoms in some studies. ClinicalTrials.gov+1

• Mood / Anxiety Benefits – Emerging clinical data suggests Cerebrolysin may reduce anxiety and improve mood, likely mediated by enhanced neuroplasticity and stress resilience. PMC

• Mechanistic Support – It is thought to act by supplying neurotrophic peptides, modulating oxidative stress, reducing inflammation, and supporting synaptic plasticity and repair. Lippincott Journals+1

Key Research Benefits & Applications

• Multi-Pathway Neuroprotection: Combines neurotrophic, antioxidant, and anti-apoptotic effects, supporting neuronal survival and recovery under ischemic or degenerative conditions.

• Stroke & Traumatic Injury Recovery: Enhances motor function, neuroplasticity, and synaptic repair following cerebral ischemia and traumatic brain injury.

• Cognitive Support in Dementia Models: Demonstrates improvements in memory, attention, and executive function in Alzheimer’s and vascular dementia research.

• Neurotrophic Factor Mimicry: Imitates the action of BDNF and GDNF, promoting neuronal growth, neurite extension, and synaptic connectivity.

• Mitochondrial & Oxidative Regulation: Reduces oxidative stress and excitotoxic damage, improving mitochondrial energy metabolism and neuronal efficiency.

• Translational Relevance: Serves as a model for studying broad-spectrum neuroprotective strategies and multi-component peptide therapeutics.

Presentation & Handling

• Form: Supplied as lyophilized peptide in sterile vial.
• Reconstitution: Use bacteriostatic water or 2% procaine; swirl gently (do not shake vigorously).
• Storage: Store at –20 °C, protected from light and moisture. After reconstitution, use according to research protocols and handle under sterile conditions.

Intended Use

For research purposes only. Must be handled in accordance with institutional protocols and ethical guidelines.