Components: GHK-Cu + TB-500 + BPC-157 + KPV
Format: Quad-Peptide Synergistic Blend
Chemical Description
KLOW is a co-lyophilized formulation containing four distinct bioactive peptides, each selected for specific receptor-ligand interactions:
1. GHK-Cu: Copper-binding tripeptide involved in collagen synthesis signaling.
2. TB-500: Actin-sequestering peptide fraction influencing cell migration.
3. BPC-157: Pentadecapeptide studied for its effects on angiogenic markers (VEGF).
4. KPV: C-terminal fragment of alpha-MSH, utilized in models of cytokine modulation.
This blend allows researchers to model complex, multi-variable cellular responses in a single experimental medium.
Research Applications
This multi-pathway blend is strictly for laboratory research use in the study of:
- Synergistic Cytokine Modulation: Investigation of NF-κB pathway inhibition and downstream reduction of inflammatory markers (IL-6, TNF-α) in macrophage cultures.
- Extracellular Matrix Remodeling: In vitro analysis of fibroblast proliferation rates and collagen deposition dynamics.
- Angiogenic Signaling: Research into the combined effects of copper transport and VEGF upregulation on endothelial cell tube formation.
Technical Specifications
- Composition: GHK-Cu, TB-500, BPC-157, KPV (Lys-Pro-Val)
- Purity: >99% (determined by HPLC for each component)
- Appearance: Lyophilized Powder (Light Blue tint due to GHK-Cu)
- Solubility: Soluble in bacteriostatic water
Presentation & Handling
- Form: Supplied as lyophilized peptide in sterile vial.
- Reconstitution: Use bacteriostatic water or 2% procaine; swirl gently (do not shake vigorously).
- Storage: Store at –20 °C, protected from light and moisture. After reconstitution, use according to research protocols and handle under sterile conditions.
Disclaimer: For Research Purposes Only
This content is provided strictly for laboratory research purposes and does not constitute an endorsement or recommendation for any non-laboratory application. The information provided regarding specific peptides is for educational and informational purposes only and must not be construed as medical, clinical, or legal guidance, nor as an encouragement for use in humans or animals.
Peptides described here are solely for use in structured scientific study by qualified researchers. We advise consulting with laboratory safety officers or research experts prior to handling these materials. The expectation of responsible, ethical utilization of this information for legitimate investigative and scholarly objectives is paramount. This notice governs all content on this site.