PT-141 (Bremelanotide) Acetate | 10mg
CAS Number: 189691-06-3
Product Overview
PT-141 (Bremelanotide) is a synthetic, cyclic heptapeptide lactam analog of the endogenous α-Melanocyte Stimulating Hormone (α-MSH). This high-purity reagent is utilized in laboratory settings to study the activation of melanocortin receptors.
The structural cyclization via a lactam bridge provides significant metabolic stability, making it a preferred subject for in vitro studies focusing on receptor binding affinity and downstream cAMP signaling pathways.
Technical Specifications
- Chemical Formula: C50H68N14O10
- Molecular Weight: 1025.2 g/mol
- Sequence: Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH
- Purity: ≥ 99% (HPLC Verified)
- Format: Lyophilized White Powder
Research Applications
This compound is strictly synthesized for laboratory research and the investigation of:
- Central Neuromodulation: Analysis of neuronal activation within the Medial Preoptic Area (MPOA).
- Receptor Selectivity: Comparative profiling between MC1R, MC3R, and MC4R signaling pathways.
- Neuroendocrine Markers: Study of hypothalamic-pituitary axis modulation in mammalian models.
Presentation & Handling
- Form: Supplied as lyophilized peptide in sterile vial.
- Reconstitution: Use bacteriostatic water or 2% procaine; swirl gently (do not shake vigorously).
- Storage: Store at –20 °C, protected from light and moisture. After reconstitution, use according to research protocols and handle under sterile conditions.
Disclaimer: For Research Purposes Only
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Peptides described here are solely for use in structured scientific study by qualified researchers. We advise consulting with laboratory safety officers or research experts prior to handling these materials. The expectation of responsible, ethical utilization of this information for legitimate investigative and scholarly objectives is paramount. This notice governs all content on this site.