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CJC-1295 (NO DAC) + Ipamorelin
  • CJC-1295 (NO DAC) + Ipamorelin
  • CJC-1295 (NO DAC) + Ipamorelin
CJC-1295 (NO DAC) + Ipamorelin
$ 4,000.00 $ 4,500.00
$ 4,000.00 MXN
$ 3,400.00 MXN

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Concentration

This formulation is a dual-peptide research blend combining CJC-1295 No DAC (Modified GRF 1-29) and Ipamorelin. It is designed to investigate the synergistic activation of the Growth Hormone-Releasing Hormone (GHRH) receptor and the Ghrelin Receptor (GHS-R1a) in pituitary somatotroph models. This blend is utilized to model physiologic, pulsatile signal transduction and downstream IGF-1 pathway modulation in vitro. Supplied as a high-purity (>99%) lyophilized reagent strictly for laboratory analysis.

Reconstitution Volume:
2 mL

Type of Diluent:
Bacteriostatic Water

Components: CJC-1295 No DAC + Ipamorelin
Format: Dual-Receptor Secretagogue Blend

Chemical Description

This research blend combines two distinct peptide analogues to target complementary signaling pathways:
1. CJC-1295 No DAC: A tetrasubstituted analogue of GHRH (1-29) that binds to the GHRH receptor to stimulate cAMP production.
2. Ipamorelin: A pentapeptide ghrelin mimetic that selectively binds to the GHS-R1a receptor to trigger intracellular calcium release.
When co-administered in vitro, these compounds exhibit a synergistic effect on somatotroph depolarization, creating a highly specific model for studying amplified pulsatile signaling without the interference of cortisol or prolactin release.

Research Applications

This synergistic blend is strictly for laboratory research use in the study of:

  • Dual-Receptor Agonism: Investigation of the non-linear amplification of signal transduction when GHRH and GHS-R1a pathways are activated simultaneously.
  • Pulsatile Secretion Dynamics: Modeling physiologic vs. non-physiologic secretory bursts in pituitary cell cultures using short-half-life ligands.
  • Cellular Metabolism: In vitro analysis of downstream effects on IGF-1 mRNA transcription and nutrient partitioning markers in adipocyte and myocyte co-cultures.

Technical Specifications

  • Concentration: 5mg CJC-1295 No DAC + 5mg Ipamorelin (10mg Total)
  • Purity: >99% (determined by HPLC for each component)
  • Appearance: Lyophilized White Powder
  • Solubility: Soluble in bacteriostatic water or saline
No analysis is available for this product.

Presentation & Handling

  • Form: Supplied as lyophilized peptide in sterile vial.
  • Reconstitution: Use bacteriostatic water or 2% procaine; swirl gently (do not shake vigorously).
  • Storage: Store at –20 °C, protected from light and moisture. After reconstitution, use according to research protocols and handle under sterile conditions.

Disclaimer: For Research Purposes Only

This content is provided strictly for laboratory research purposes and does not constitute an endorsement or recommendation for any non-laboratory application. The information provided regarding specific peptides is for educational and informational purposes only and must not be construed as medical, clinical, or legal guidance, nor as an encouragement for use in humans or animals.


Peptides described here are solely for use in structured scientific study by qualified researchers. We advise consulting with laboratory safety officers or research experts prior to handling these materials. The expectation of responsible, ethical utilization of this information for legitimate investigative and scholarly objectives is paramount. This notice governs all content on this site.

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