Skip to product information
CJC-1295 (NO DAC)
  • CJC-1295 (NO DAC)
  • CJC-1295 (NO DAC)
CJC-1295 (NO DAC)
$ 2,000.00 $ 2,500.00
$ 2,000.00 MXN
$ 1,700.00 MXN

Auto-renews, skip or cancel anytime.

To add to cart, go to the product page and select a purchase option
Concentration

CJC-1295 No DAC (Tetrasubstituted GRF 1-29) is a synthetic peptide analogue of the Growth Hormone-Releasing Hormone (GHRH). It is chemically modified to enhance enzymatic stability while maintaining a short half-life (~30 minutes), distinguishing it from long-acting variants. This compound is utilized in laboratory research to model physiologic, pulsatile GHRH receptor signaling and to investigate pituitary somatotroph kinetics in vitro. Strictly for laboratory use.

Reconstitution Volume:
2 mL

Type of Diluent:
Bacteriostatic Water

CAS Number: 863288-34-0
Sequence: Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-NH2

Chemical Description

CJC-1295 No DAC (also known as Modified GRF 1-29) is a synthetic, tetrasubstituted analogue of the endogenous peptide GHRH(1-29). The structural modifications involve specific amino acid substitutions designed to increase resistance to cleavage by the enzyme Dipeptidyl Peptidase-4 (DPP-IV). Unlike the "DAC" variant, this peptide lacks the Drug Affinity Complex moiety, resulting in a kinetic profile that allows for the study of rapid receptor activation and clearance mechanisms in vitro.

Research Applications

This compound is strictly for laboratory research use in the study of:

  • Pulsatile Receptor Signaling: Research into the non-continuous activation of the GHRH receptor on anterior pituitary cells.
  • Enzymatic Stability Assays: Comparative analysis of peptide degradation rates in the presence of plasma proteases versus native GHRH.
  • Somatotroph Kinetics: In vitro measurement of cyclic AMP (cAMP) accumulation and downstream signal transduction in somatotroph cultures.

Technical Specifications

  • Molecular Formula: C152H252N44O42
  • Molecular Weight: 3367.9 g/mol
  • Purity: >99% (determined by HPLC)
  • Appearance: Lyophilized White Powder
No analysis is available for this product.

Presentation & Handling

  • Form: Supplied as lyophilized peptide in sterile vial.
  • Reconstitution: Use bacteriostatic water or 2% procaine; swirl gently (do not shake vigorously).
  • Storage: Store at –20 °C, protected from light and moisture. After reconstitution, use according to research protocols and handle under sterile conditions.

Disclaimer: For Research Purposes Only

This content is provided strictly for laboratory research purposes and does not constitute an endorsement or recommendation for any non-laboratory application. The information provided regarding specific peptides is for educational and informational purposes only and must not be construed as medical, clinical, or legal guidance, nor as an encouragement for use in humans or animals.


Peptides described here are solely for use in structured scientific study by qualified researchers. We advise consulting with laboratory safety officers or research experts prior to handling these materials. The expectation of responsible, ethical utilization of this information for legitimate investigative and scholarly objectives is paramount. This notice governs all content on this site.

You may also like