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GHRP-6
  • GHRP-6
  • GHRP-6
GHRP-6
$ 1,800.00 $ 2,000.00
$ 1,800.00 MXN
$ 1,530.00 MXN

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Concentration

GHRP-6 (Growth Hormone Releasing Peptide-6) is a synthetic hexapeptide that functions as a selective agonist of the Growth Hormone Secretagogue Receptor (GHSR-1a). In biochemical research, it is utilized to model the intracellular signaling cascades of endogenous ghrelin, specifically investigating the activation of the Phospholipase C (PLC) pathway and calcium ion influx in pituitary somatotrophs. Supplied as a high-purity (>99%) lyophilized reagent strictly for in vitro receptor kinetics analysis. Strictly for laboratory use only.

Reconstitution Volume:
2 mL

Type of Diluent:
Bacteriostatic Water

CAS Number: 87616-84-0
Sequence: His-D-Trp-Ala-Trp-D-Phe-Lys-NH2

Chemical Description

GHRP-6 is a synthetic Met-enkephalin analogue comprising six amino acids (hexapeptide). Unlike endogenous Growth Hormone-Releasing Hormone (GHRH), GHRP-6 does not act on the GHRH receptor but instead binds selectively to the Ghrelin Receptor (GHSR-1a). Biochemically, this binding event triggers a signal transduction cascade involving Protein Kinase C (PKC) and IP3, leading to the depolarization of somatotroph cells and the release of growth hormone vesicles in vitro. It serves as a fundamental model for studying non-GHRH mediated endocrine regulation.

Research Applications

This compound is strictly for laboratory research use in the study of:

  • G-Protein Coupled Receptor (GPCR) Signaling: Investigation of the conformational changes in the GHSR-1a receptor upon ligand binding.
  • Ghrelin Mimetic Assays: Research into the feedback loops of gastric hormone signaling and cellular energy homeostasis markers.
  • Cytoprotective Pathways: In vitro analysis of the peptide's influence on cell survival signaling (PI3K/Akt pathway) in cardiomyocyte or neuronal cell cultures under oxidative stress.

Technical Specifications

  • Molecular Formula: C46H56N12O6
  • Molecular Weight: 873.01 g/mol
  • Purity: >99% (determined by HPLC)
  • Appearance: Lyophilized White Powder
No analysis is available for this product.

Presentation & Handling

  • Form: Supplied as lyophilized peptide in sterile vial.
  • Reconstitution: Use bacteriostatic water or 2% procaine; swirl gently (do not shake vigorously).
  • Storage: Store at –20 °C, protected from light and moisture. After reconstitution, use according to research protocols and handle under sterile conditions.

Disclaimer: For Research Purposes Only

This content is provided strictly for laboratory research purposes and does not constitute an endorsement or recommendation for any non-laboratory application. The information provided regarding specific peptides is for educational and informational purposes only and must not be construed as medical, clinical, or legal guidance, nor as an encouragement for use in humans or animals.


Peptides described here are solely for use in structured scientific study by qualified researchers. We advise consulting with laboratory safety officers or research experts prior to handling these materials. The expectation of responsible, ethical utilization of this information for legitimate investigative and scholarly objectives is paramount. This notice governs all content on this site.

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