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Ipamorelin
  • Ipamorelin
  • Ipamorelin
Ipamorelin
$ 1,950.00 $ 2,500.00
$ 1,950.00 MXN
$ 1,657.50 MXN

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Concentration

Ipamorelin is a synthetic pentapeptide that functions as a highly selective agonist of the Growth Hormone Secretagogue Receptor (GHS-R1a). Unlike earlier secretagogues, it demonstrates a unique pharmacological profile with minimal affinity for adrenocorticotropic (ACTH) or prolactin signaling pathways. In endocrine research, it is utilized to model pure somatotropic signal transduction and pulsatile secretion kinetics without confounding stress hormone variables. Supplied as a high-purity (>99%) lyophilized reagent strictly for laboratory analysis.

Reconstitution Volume:
2 mL

Type of Diluent:
Bacteriostatic Water

CAS Number: 170851-70-4
Sequence: Aib-His-D-2-Nal-D-Phe-Lys-NH2

Chemical Description

Ipamorelin is a synthetic pentapeptide distinct from other growth hormone-releasing peptides (GHRPs) due to its enhanced specificity. Structurally, it incorporates Aib (2-aminoisobutyric acid) and 2-Naphthylalanine, modifications that confer resistance to dipeptidyl peptidase degradation. Biochemically, Ipamorelin acts as a selective agonist for the ghrelin receptor (GHS-R1a). Its defining characteristic in research is its lack of cross-reactivity with receptors controlling ACTH (cortisol) and Prolactin release, allowing for the isolation of specific somatotropic pathways in vitro.

Research Applications

This compound is strictly for laboratory research use in the study of:

  • Selective Receptor Agonism: Investigation of GHS-R1a binding kinetics and intracellular calcium mobilization without the interference of off-target neuroendocrine signaling.
  • Pulsatile Secretion Dynamics: Modeling physiologic growth hormone pulses in pituitary cell cultures to study receptor desensitization rates compared to non-selective ligands.
  • Gastric Motility Signaling: Research into the modulation of gastric smooth muscle contraction pathways via ghrelin receptor activation.

Technical Specifications

  • Molecular Formula: C38H49N9O5
  • Molecular Weight: 711.85 g/mol
  • Purity: >99% (determined by HPLC)
  • Appearance: Lyophilized White Powder
  • Format: 10mg Vial
No analysis is available for this product.

Presentation & Handling

  • Form: Supplied as lyophilized peptide in sterile vial.
  • Reconstitution: Use bacteriostatic water or 2% procaine; swirl gently (do not shake vigorously).
  • Storage: Store at –20 °C, protected from light and moisture. After reconstitution, use according to research protocols and handle under sterile conditions.

Disclaimer: For Research Purposes Only

This content is provided strictly for laboratory research purposes and does not constitute an endorsement or recommendation for any non-laboratory application. The information provided regarding specific peptides is for educational and informational purposes only and must not be construed as medical, clinical, or legal guidance, nor as an encouragement for use in humans or animals.


Peptides described here are solely for use in structured scientific study by qualified researchers. We advise consulting with laboratory safety officers or research experts prior to handling these materials. The expectation of responsible, ethical utilization of this information for legitimate investigative and scholarly objectives is paramount. This notice governs all content on this site.

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