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Ipamorelin
  • Ipamorelin
  • Ipamorelin
Ipamorelin
$ 2,100.00 $ 2,500.00
Concentration

Ipamorelin is a third-generation growth hormone secretagogue (GHRP) engineered for selectivity and precision. Unlike earlier GHRPs, it stimulates GH release without significantly affecting cortisol, prolactin, or aldosterone, making it one of the cleanest tools for endocrine research. In preclinical studies, it has been investigated for roles in muscle growth, anti-aging, bone density, and gastrointestinal recovery, offering researchers a versatile option for studying regeneration, metabolism, and hormonal dynamics. Supplied as a 10 mg high-purity lyophilized vial, ready for reconstitution and advanced laboratory use.

PEPTIDES4ALL Ipamorelin – Selective Growth Hormone Secretagogue for Endocrine & Regenerative Research

PEPTIDES4ALL Ipamorelin is a synthetic pentapeptide (Aib-His-D-2-Nal-D-Phe-Lys-NH₂) presented in 10 mg lyophilized vials, designed for precise, research-grade exploration of growth hormone (GH) modulation. As a highly selective GH secretagogue, Ipamorelin binds to ghrelin (GHS-R) receptors to stimulate natural GH release while minimizing unwanted hormonal interactions.

Unlike earlier generations of growth hormone-releasing peptides, Ipamorelin exhibits minimal influence on cortisol or prolactin, allowing researchers to study targeted GH elevation without systemic side effects. Preclinical research highlights its potential in muscle repair, bone growth, metabolic regulation, and cellular rejuvenation.

This high-purity formulation offers a controlled and reproducible platform for investigating endocrine balance, anabolic recovery, and anti-aging pathways through GH-mediated mechanisms.

Scientific Evidence & Research Findings

  • Ipamorelin was developed as a selective GH secretagogue. In vivo and in vitro pharmacology studies show that it stimulates GH release with potency comparable to GHRP-6, but unlike many GHRPs, it does not significantly induce ACTH, cortisol, or prolactin. PubMed+2Wiley Online Library+2
  • In rat pituitary cell studies, ipamorelin elicited GH secretion with similar efficacy to GHRP-6 (EC₅₀ ~1.3 nmol/L; E_max ~85%) PubMed+1
  • In swine, ipamorelin triggered GH release (ED₅₀ ~2.3 nmol/kg) without significant effects on cortisol or ACTH—even at doses >200× the GH-releasing dose. ResearchGate+2PubMed+2
  • Because of its selectivity, ipamorelin is often described as a “clean” GH secretagogue, ideal when researchers want to avoid confounding hormonal changes (e.g. cortisol or prolactin shifts) in their protocols. Wiley Online Library+2Body of Harmony+2
  • Some animal studies also show that chronic ipamorelin administration improves weight gain and basal GH secretion without desensitization in certain models. ResearchGate

Key Research Benefits & Applications

  • Selective GH Stimulation — Promotes growth hormone release without significantly raising ACTH, cortisol, or prolactin.
  • Cleaner Hormonal Profile — Reduced risk of endocrine interference compared to other GH secretagogues.
  • Short Half-Life with Pulsatile Effect — Enables precise timing studies of GH kinetics.
  • Support for Metabolic / Regenerative Research — Useful in research on aging, muscle growth/repair, metabolic function, and endocrine regulation.
  • High Purity & Consistency — Lyophilized for stability, designed for reproducible results.

Presentation & Handling

  • Form: Supplied as lyophilized peptide in sterile vial.
  • Reconstitution: Use bacteriostatic water or 2% procaine; swirl gently (do not shake vigorously).
  • Storage: Store at –20 °C, protected from light and moisture. After reconstitution, use according to research protocols and handle under sterile conditions.

Intended Use

For research purposes only. Must be handled in accordance with institutional protocols and ethical guidelines.

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