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NAD+
  • NAD+
  • NAD+
NAD+
$ 3,500.00 $ 4,000.00
$ 3,500.00 MXN
$ 2,975.00 MXN

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Concentration

NAD+ (Nicotinamide Adenine Dinucleotide, Oxidized Form) is a pivotal coenzyme found in all living cells. In biochemical research, it serves as an essential electron acceptor in redox reactions and as a substrate for enzymes such as poly(ADP-ribose) polymerases (PARPs) and sirtuins. This high-purity reagent is utilized in laboratory settings to investigate dehydrogenase enzymatic kinetics and mitochondrial electron transport chain dynamics in vitro. Supplied as a lyophilized hygroscopic powder strictly for laboratory analysis. Strictly for laboratory use only.

Reconstitution Volume:
5 mL

Type of Diluent:
Bacteriostatic Water

CAS Number: 53-84-9
Format: Oxidized Coenzyme (Dinucleotide)

Chemical Description

Nicotinamide Adenine Dinucleotide (NAD+) is a dinucleotide coenzyme consisting of an adenine base and a nicotinamide base joined by a pair of phosphate groups. Chemically, it acts as a primary electron carrier in cellular metabolism, alternating between its oxidized (NAD+) and reduced (NADH) forms. It functions as an obligate cofactor for varying dehydrogenase enzymes and serves as the sole substrate for NAD-dependent signaling enzymes, including Sirtuins (Class III histone deacetylases) and PARPs, regulating post-translational protein modification in vitro.

Research Applications

This coenzyme is strictly for laboratory research use in the study of:

  • Enzymatic Kinetics: Measurement of reaction rates for NAD-dependent dehydrogenases (e.g., Lactate Dehydrogenase, Malate Dehydrogenase) via spectrophotometric analysis at 340 nm.
  • Sirtuin Deacetylation Assays: Investigation of the NAD+ dependence of Sirtuin-mediated histone deacetylation and chromatin silencing mechanisms.
  • DNA Repair Signaling: In vitro analysis of PARP-1 activity and poly(ADP-ribosyl)ation in response to genotoxic stress models.

Technical Specifications

  • Molecular Formula: C21H27N7O14P2
  • Molecular Weight: 663.43 g/mol
  • Purity: >99% (determined by HPLC)
  • Appearance: Lyophilized White Hygroscopic Powder
No analysis is available for this product.

Presentation & Handling

  • Form: Supplied as lyophilized peptide in sterile vial.
  • Reconstitution: Use bacteriostatic water or 2% procaine; swirl gently (do not shake vigorously).
  • Storage: Store at –20 °C, protected from light and moisture. After reconstitution, use according to research protocols and handle under sterile conditions.

Disclaimer: For Research Purposes Only

This content is provided strictly for laboratory research purposes and does not constitute an endorsement or recommendation for any non-laboratory application. The information provided regarding specific peptides is for educational and informational purposes only and must not be construed as medical, clinical, or legal guidance, nor as an encouragement for use in humans or animals.


Peptides described here are solely for use in structured scientific study by qualified researchers. We advise consulting with laboratory safety officers or research experts prior to handling these materials. The expectation of responsible, ethical utilization of this information for legitimate investigative and scholarly objectives is paramount. This notice governs all content on this site.

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