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NAD+
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Concentration

NAD⁺ – Core Coenzyme for Cellular Energy, DNA Repair & Longevity Research

NAD⁺ (Nicotinamide Adenine Dinucleotide) is a vital redox coenzyme found in every living cell and essential to energy metabolism, mitochondrial performance, and genomic stability. It fuels critical processes such as ATP production, DNA repair, and sirtuin activation, forming the biochemical foundation for cellular health and resilience.

As NAD⁺ levels naturally decline with age and metabolic stress, restoring or maintaining this coenzyme has become a key focus in metabolic, neurodegenerative, and longevity research. Studies have explored its role in enhancing mitochondrial efficiency, supporting stress resistance, and promoting healthy aging at the cellular level.

Formulated in high-purity, research-grade quality, NAD⁺ offers scientists a dependable compound for investigating energy regulation, DNA repair mechanisms, and advanced anti-aging pathways.

PEPTIDES4ALL NAD+ (Nicotinamide Adenine Dinucleotide) – Cellular Energy & Longevity Research Coenzyme

PEPTIDES4ALL NAD+ represents one of the most fundamental molecules in modern biomedical research—a core coenzyme essential for cellular energy transfer, redox balance, and genomic maintenance. Found in every living cell, NAD+ fuels the chemical reactions that sustain life, supporting the conversion of nutrients into ATP, the universal energy currency of the cell.

Beyond its role in energy metabolism, NAD+ has emerged as a central node in cellular resilience, DNA repair, and longevity regulation. It serves as a substrate for critical enzyme families such as sirtuins and poly(ADP-ribose) polymerases (PARPs), both of which are integral to mitochondrial function, stress resistance, and genomic integrity.

As research in aging biology advances, NAD+ has become a cornerstone of longevity science—its decline with age and chronic stress is now recognized as a key biomarker of metabolic and cellular dysfunction. Preclinical and translational studies have linked NAD+ restoration to improved metabolic flexibility, neuroprotection, cardiovascular performance, and inflammation control, establishing it as a pivotal molecule in the exploration of healthy aging and regenerative medicine.

The PEPTIDES4ALL NAD+ lyophilized formulation provides researchers with a high-purity, stabilized coenzyme source for exploring the intricate pathways of cellular energy production, redox biology, and DNA repair, contributing to the growing body of work investigating how NAD+ modulation may enhance longevity and systemic vitality.


Scientific Evidence & Research Findings

  • NAD+ participates in oxidative phosphorylation, glycolysis, and the citric acid cycle, helping convert nutrients into ATP.

  • It acts as a cofactor for sirtuin proteins, which regulate metabolic health, stress resistance, and mitochondrial function.

  • NAD+ also plays a role in DNA damage repair via PARP enzyme systems and supports genomic stability.

  • In aging and disease, NAD+ levels decline; supplementation strategies (e.g., NAD+ precursors) are being studied for therapeutic potential. Nature+2ScienceDirect+2

  • Clinical reviews show that NAD+ and NADH interventions are generally well tolerated, with modest improvements in metabolic markers, but more high-powered trials are needed. PubMed+1


Key Research Benefits & Applications

  • Cellular Energy Restoration: Serves as an essential coenzyme in ATP generation through glycolysis, the citric acid cycle, and oxidative phosphorylation, providing a foundational model for studying bioenergetic metabolism.

  • Mitochondrial Function & Redox Balance: Enhances mitochondrial respiration and antioxidant defense by maintaining NAD⁺/NADH ratios critical for redox homeostasis and oxidative stress regulation.

  • Sirtuin & PARP Activation: Acts as a substrate for sirtuins (SIRT1–7) and poly(ADP-ribose) polymerases (PARPs)—key enzyme systems that control DNA repair, gene silencing, metabolic adaptation, and stress resistance.

  • Genomic Maintenance & DNA Repair: Supports genome stability and chromatin remodeling by fueling NAD⁺-dependent repair mechanisms involved in cellular protection and aging research.

  • Metabolic Health & Longevity Research: Restores NAD⁺ pools depleted by aging, inflammation, or metabolic stress, offering a model for interventions in neuroprotection, cardiovascular performance, and systemic rejuvenation.

  • Integration in Combined Research Strategies: Complements precursor-based interventions (e.g., NMN, NR) or metabolic cofactor studies, providing a direct framework for exploring NAD⁺ replenishment and cellular resilience mechanisms.


Presentation & Handling

  • Form: Supplied as lyophilized peptide in sterile vial.
  • Reconstitution: Use bacteriostatic water or 2% procaine; swirl gently (do not shake vigorously).
  • Storage: Store at –20 °C, protected from light and moisture. After reconstitution, use according to research protocols and handle under sterile conditions.

Intended Use

For research purposes only. Must be handled in accordance with institutional protocols and ethical guidelines.

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