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SLU-PP-332
  • SLU-PP-332
  • SLU-PP-332
SLU-PP-332
$ 2,000.00 $ 2,300.00
$ 2,000.00 MXN
$ 1,700.00 MXN

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Concentration

SLU-PP-332 is a synthetic small molecule designed to function as a pan-agonist for the Estrogen-Related Receptors (ERRα, ERRβ, and ERRγ). In laboratory research, this compound is utilized to investigate the transcriptional regulation of mitochondrial biogenesis and oxidative phosphorylation pathways within skeletal muscle cell cultures. Supplied as a high-purity (>99%) lyophilized reagent strictly for in vitro metabolic signaling analysis. Strictly for laboratory use.

Reconstitution Volume:
2 mL

Type of Diluent:
Bacteriostatic Water

CAS Number: 2379502-67-5
Format: Synthetic Nuclear Receptor Ligand (Small Molecule)

Chemical Description

SLU-PP-332 is a synthetic compound characterized as a pan-agonist of the Estrogen-Related Receptor (ERR) family, with high affinity for ERRα, ERRβ, and ERRγ isoforms. Unlike natural ligands, this small molecule is designed to stabilize the active conformation of these nuclear receptors, thereby promoting the recruitment of coactivators such as PGC-1α. It is widely used in biochemical research to model the upregulation of gene networks governing cellular energy homeostasis and mitochondrial respiration in vitro.

Research Applications

This compound is strictly for laboratory research use in the study of:

  • Mitochondrial Biogenesis: Investigation of the transcriptional activation of oxidative phosphorylation genes (OXPHOS) in myocyte cultures.
  • Metabolic Phenotyping: Research into the conversion of skeletal muscle fiber types (glycolytic to oxidative) via nuclear receptor modulation.
  • Cellular Respiration Assays: In vitro measurement of maximal respiration rates and ATP production dynamics in metabolic cell models.

Technical Specifications

  • Molecular Formula: C20H16N2O3
  • Molecular Weight: 332.35 g/mol
  • Purity: >99% (determined by HPLC)
  • Appearance: Lyophilized White to Off-White Powder
No analysis is available for this product.

Presentation & Handling

  • Form: Supplied as lyophilized peptide in sterile vial.
  • Reconstitution: Use bacteriostatic water or 2% procaine; swirl gently (do not shake vigorously).
  • Storage: Store at –20 °C, protected from light and moisture. After reconstitution, use according to research protocols and handle under sterile conditions.

Disclaimer: For Research Purposes Only

This content is provided strictly for laboratory research purposes and does not constitute an endorsement or recommendation for any non-laboratory application. The information provided regarding specific peptides is for educational and informational purposes only and must not be construed as medical, clinical, or legal guidance, nor as an encouragement for use in humans or animals.


Peptides described here are solely for use in structured scientific study by qualified researchers. We advise consulting with laboratory safety officers or research experts prior to handling these materials. The expectation of responsible, ethical utilization of this information for legitimate investigative and scholarly objectives is paramount. This notice governs all content on this site.

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