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SS-31
  • SS-31
  • SS-31
SS-31
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$ 2,000.00 MXN
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Concentration

SS-31 (Elamipretide) is a cell-permeable synthetic tetrapeptide designed to selectively target the Inner Mitochondrial Membrane (IMM). It binds specifically to cardiolipin, a phospholipid essential for cristae curvature, to stabilize electron transport chain supercomplexes. In laboratory settings, this compound is utilized to investigate mitochondrial bioenergetics, ROS scavenging kinetics, and membrane potential maintenance. Supplied as a high-purity (>99%) lyophilized reagent. Strictly for laboratory use only. Strictly for laboratory use.

Reconstitution Volume:
2 mL

Type of Diluent:
Bacteriostatic Water

CAS Number: 736992-21-5
Sequence: D-Arg-Dmt-Lys-Phe-NH2 (Szeto-Schiller-31)

Chemical Description

SS-31 (Elamipretide) is a water-soluble, aromatic-cationic tetrapeptide belonging to the Szeto-Schiller (SS) peptide family. It is engineered to penetrate the cell membrane and localize to the Inner Mitochondrial Membrane (IMM). Chemically, SS-31 interacts electrostatically with cardiolipin (CL), stabilizing membrane curvature and preventing the peroxidase activity of the cytochrome c/cardiolipin complex. This mechanism is studied for its role in optimizing electron flux and reducing electron leakage during oxidative phosphorylation in vitro.

Research Applications

This mitochondria-targeted peptide is strictly for laboratory research use in the study of:

  • Cardiolipin Stabilization: Investigation of phospholipid-protein interactions and the structural integrity of mitochondrial cristae.
  • ROS Scavenging Kinetics: In vitro analysis of reactive oxygen species reduction at the source (Electron Transport Chain) without affecting cellular signaling.
  • Bioenergetics Profiling: Measurement of ATP production rates and mitochondrial respiration efficiency (Oxygen Consumption Rate - OCR) in metabolic cell models.

Technical Specifications

  • Molecular Formula: C32H49N9O5
  • Molecular Weight: 639.8 g/mol
  • Purity: >99% (determined by HPLC)
  • Appearance: Lyophilized White Powder
No analysis is available for this product.

Presentation & Handling

  • Form: Supplied as lyophilized peptide in sterile vial.
  • Reconstitution: Use bacteriostatic water or 2% procaine; swirl gently (do not shake vigorously).
  • Storage: Store at –20 °C, protected from light and moisture. After reconstitution, use according to research protocols and handle under sterile conditions.

Disclaimer: For Research Purposes Only

This content is provided strictly for laboratory research purposes and does not constitute an endorsement or recommendation for any non-laboratory application. The information provided regarding specific peptides is for educational and informational purposes only and must not be construed as medical, clinical, or legal guidance, nor as an encouragement for use in humans or animals.


Peptides described here are solely for use in structured scientific study by qualified researchers. We advise consulting with laboratory safety officers or research experts prior to handling these materials. The expectation of responsible, ethical utilization of this information for legitimate investigative and scholarly objectives is paramount. This notice governs all content on this site.

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