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TB-500
  • TB-500
  • TB-500
TB-500
$ 2,000.00 $ 2,500.00
Concentration

TB-500 is a synthetic peptide fragment of Thymosin Beta-4, widely studied for its role in tissue regeneration, wound healing, and angiogenesis. Preclinical models show accelerated recovery, reduced inflammation, and enhanced vascular support, making TB-500 a versatile research tool for fibrosis, oxidative stress, and musculoskeletal repair studies. Offered in 10 mg lyophilized vials, it provides high stability and reproducibility for laboratory protocols.

PEPTIDES4ALL TB-500 – Synthetic Thymosin Beta-4 Fragment for Tissue Repair & Regenerative Research

PEPTIDES4ALL TB-500 is a synthetic fragment of Thymosin Beta-4 (Tβ4), supplied in 10 mg lyophilized vials for high-precision scientific use. This research-grade peptide is designed to advance studies in tissue regeneration, angiogenesis, inflammation control, and cellular protection.

Preclinical research suggests that TB-500 promotes actin regulation, facilitating cell migration and repair across muscle, tendon, and skin tissues. It has been explored for its potential to enhance wound healing, reduce oxidative damage, and support recovery from musculoskeletal injury.

With exceptional purity and stability, PEPTIDES4ALL TB-500 provides a consistent platform for investigators studying regenerative medicine, recovery biology, and anti-inflammatory mechanisms.

Scientific Evidence & Research Findings

Thymosin Beta-4 is a naturally occurring, 43-amino-acid peptide known for its role in cell motility, angiogenesis, wound healing, and cytoprotection. Wikipedia+2Frontiers+2

  • In rodent wound models, Tβ4 accelerated re-epithelialization by up to ~61% at day 7, increased angiogenesis and collagen deposition, and stimulated keratinocyte migration ~2–3× vs control. PubMed+1
  • Tβ4 promotes new blood vessel formation (angiogenesis) in normal and aged animals, supporting tissue repair even in lower-regeneration scenarios. PubMed+1
  • In endothelial progenitor cell (EPC) studies, Tβ4 enhanced VEGF expression and paracrine signaling, boosting angiogenesis through the Akt/eNOS pathway. Spandidos Publications
  • In diabetic-induced endothelial dysfunction models, Tb4 improved cell viability, reduced senescence, lowered endothelin-1 and MMP-1 secretion, and enhanced reparative angiogenic potency in vivo. BioMed Central
  • Recent reviews also highlight Tβ4’s anti-fibrotic, antioxidant, and anti-inflammatory effects in multiple organ injury models (e.g. heart, liver, kidney). Frontiers

These cumulative findings position TB-500 as a versatile tool for probing mechanisms underlying tissue healing, angiogenesis, fibrosis prevention, and regenerative therapies.

Key Research Benefits & Applications

  • Angiogenesis & Vascular Support – Promotes blood vessel formation and supports endothelial repair via VEGF induction and paracrine signaling.
  • Accelerated Wound Healing – Enhances re-epithelialization, collagen deposition, keratinocyte migration, and wound contraction.
  • Cytoprotection & Anti-Inflammatory – Modulates inflammatory cytokines, reduces oxidative damage, and offers anti-fibrotic properties.
  • Regenerative Potential – Useful for modeling repair in muscle, tendon, ligament, myocardial, hepatic, or neural tissues.
  • High Purity & Stability – Supplied as lyophilized powder for shelf stability; designed for consistent, reproducible research outcomes.
  • Dose Flexibility – Offered in 5 mg and 10 mg vials to allow titration across experimental designs.

Presentation & Handling

  • Form: Supplied as lyophilized peptide in sterile vial.
  • Reconstitution: Use bacteriostatic water or 2% procaine; swirl gently (do not shake vigorously).
  • Storage: Store at –20 °C, protected from light and moisture. After reconstitution, use according to research protocols and handle under sterile conditions.

Intended Use

For research purposes only. Must be handled in accordance with institutional protocols and ethical guidelines.

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