Tesamorelin Acetate
CAS Number: 218949-48-5
Product Overview
Tesamorelin Acetate is a synthetic peptide analogue of the endogenous growth hormone-releasing hormone (GHRH). This laboratory reagent consists of the 44 amino acid sequence of human GHRH, modified with a trans-3-hexenoic acid group at the N-terminal tyrosine residue.
This specific N-terminal modification is engineered to significantly increase metabolic stability against enzymatic degradation during in vitro assays, allowing for more accurate prolonged observation of receptor-ligand interactions.
Technical Specifications
- Chemical Formula: C221H366N72O67S
- Molecular Weight: 5135.9 g/mol
- Sequence: trans-3-Hexenoyl-[Tyr1]hGRF(1-44)NH2
- Purity: ≥ 99% (HPLC Verified)
- Physical Form: Lyophilized White Powder
Research Applications
This peptide is synthesized strictly for laboratory research and analytical studies, including:
- GHRH Receptor Agonism: Investigation of binding affinity and ligand potency in cellular models.
- Somatotroph Signaling: In vitro analysis of signal transduction pathways involving cAMP and Calcium ion channels.
- Metabolic Markers: Laboratory measurement of enzymatic activity and lipolysis markers in isolated tissue cultures.
Presentation & Handling
- Form: Supplied as lyophilized peptide in sterile vial.
- Reconstitution: Use bacteriostatic water or 2% procaine; swirl gently (do not shake vigorously).
- Storage: Store at –20 °C, protected from light and moisture. After reconstitution, use according to research protocols and handle under sterile conditions.
Disclaimer: For Research Purposes Only
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