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BAM-15
  • BAM-15
  • BAM-15
BAM-15
$ 2,100.00 $ 3,000.00
Food supplement form

BAM-15 235 mg – Oral Supplement for Metabolic & Mitochondrial Research

BAM-15 is a mitochondria-targeted protonophore studied for its role in energy metabolism, fat oxidation, and insulin sensitivity. As a mitochondrial uncoupler, BAM-15 promotes increased energy expenditure by enhancing proton leak across the mitochondrial membrane—an effect that elevates metabolic rate without stimulating appetite or compromising lean mass.

In preclinical models of diet-induced obesity, BAM-15 has been shown to reduce fat mass, reverse insulin resistance, and improve glucose utilization, highlighting its value in metabolic and mitochondrial research.

Emerging studies also suggest organ-protective effects under oxidative and inflammatory stress, as well as anti-tumor potential through modulation of cellular energy metabolism and bioenergetic stress.

Formulated in high-purity, research-grade quality (235 mg), BAM-15 offers a dependable tool for investigating metabolic regulation, mitochondrial function, and energy balance in advanced scientific studies.

PEPTIDES4ALL BAM-15 – Mitochondrial Uncoupler for Metabolic & Energetic Research

BAM-15 is a next-generation mitochondrial protonophore designed to modulate cellular energy metabolism through controlled mitochondrial uncoupling.
By partially dissipating the proton gradient across the inner mitochondrial membrane, BAM-15 increases nutrient oxidation and oxygen consumption, effectively shifting cells toward higher energy expenditure and fat utilization.

Unlike classical uncouplers such as DNP, BAM-15 exhibits favorable pharmacokinetics, oral bioavailability, and tissue selectivity, making it a valuable compound for studying obesity, insulin resistance, metabolic syndrome, organ protection, and oxidative stress.
Its balanced uncoupling profile allows energy metabolism to accelerate without triggering thermogenic toxicity, distinguishing it as a safe and precise tool for mitochondrial energetics research. Nature+2PubMed+2

Scientific Evidence & Research Findings

  • Oral Bioavailability & Anti-Obesity Efficacy — BAM-15 is orally bioavailable and in diet-induced obese mice it increased nutrient oxidation, reduced body fat, and improved insulin sensitivity, all without reducing lean mass or food intake. Nature

  • Glycemic & Metabolic Improvements — It reversed insulin resistance in tissues including liver and muscle in animal models. PubMed+1

  • Safety & Selectivity — In preclinical studies, it had minimal effects on body temperature or hematological/biochemical toxicity markers. Nature+1

  • Organ Protection & Sepsis Models — In murine sepsis models, BAM-15 improved survival, reduced acute kidney injury, and mitigated mtDNA release and neutrophil infiltration. JCI

  • Anticancer Effects — In certain cancer cell lines and xenograft models, BAM-15 suppressed proliferation, migration, and viability by forcing metabolic stress via mitochondrial uncoupling. BioMed Central

Key Research Benefits & Features

  • Mitochondrial Uncoupling & Energy Expenditure — Enhances nutrient oxidation, driving higher metabolic output and fat utilization.

  • Anti-Obesity & Metabolic Regulation — Reduces adiposity while preserving lean mass and improving insulin sensitivity.

  • Organ Protection & Inflammatory Control — Mitigates tissue injury and inflammation in sepsis, ischemia, and metabolic stress models.

  • Mitochondrial Health & Oxidative Balance — Supports studies on mitochondrial quality control, ROS signaling, and energy homeostasis.

  • Anticancer Research Potential — Induces metabolic stress and apoptosis in high-glycolytic tumor cells.

  • Translational Value — Provides a robust model for studying safe mitochondrial uncoupling as a therapeutic strategy in obesity and longevity research.

Presentation & Handling

  • Form: Oral capsules.
  • Storage: Store in a cool, dry environment, away from heat, light, and moisture.

Intended Use

For research purposes only. Must be handled in accordance with institutional laboratory standards, biosafety regulations, and ethical research protocols.

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