PEPTIDES4ALL CJC-1295 DAC – Long-Acting Growth Hormone-Releasing Hormone Analogue for GH/IGF-1 Research

PEPTIDES4ALL CJC-1295 DAC (Drug Affinity Complex) is a long-acting synthetic analogue of growth hormone-releasing hormone (GHRH), developed to provide sustained stimulation of growth hormone (GH) and insulin-like growth factor 1 (IGF-1) secretion in research models.

Through its reversible binding to serum albumin, CJC-1295 DAC significantly extends plasma half-life and bioavailability compared to native GHRH, enabling consistent and prolonged GH release for advanced scientific studies.

Presented in 10 mg lyophilized vials, this high-purity formulation ensures precision, stability, and reproducibility, supporting research focused on growth hormone modulation, metabolic regulation, cellular repair, and anti-aging pathways.

Scientific Evidence & Research Findings

• In healthy adult humans, CJC-1295 DAC has been shown to produce 2- to 10-fold increases in GH levels sustained for 6 days or more following a single dose. Oxford Academic+1
  
  
• The same clinical trials demonstrated elevated IGF-1 levels over prolonged periods, correlating with the GH response. Oxford Academic
  
  
• The half-life for CJC-1295 with DAC in humans is estimated at 6 to 8 days — significantly longer than non-DAC (which is on the order of ~30 minutes). The International Peptide Society+1
  
  
• Because of this extended action, CJC-1295 with DAC enables less frequent dosing in experimental protocols while maintaining sustained hormonal stimulation. Europe PMC
  
• Preclinical (animal) studies confirm that CJC-1295 analogues activate GHRH receptors in the anterior pituitary and elicit GH release responses consistent with their design. Physiology Journals
  

Key Research Benefits & Applications

• Extended Duration of Action
  The DAC modification allows reversible binding to albumin, which reduces rapid clearance and enables sustained GH and IGF-1 stimulation over days.
• Robust Hormonal Response
  With appropriate dosing, researchers have documented significant and sustained increases in GH and downstream IGF-1, useful for studies in metabolism, growth, tissue repair, and endocrine modulation.
• Improved Protocol Efficiency
  Because of its prolonged effect, fewer administrations are needed compared to short-acting analogs, making longitudinal study designs more feasible.
• High Purity & Stability
  Supplied in lyophilized form for better shelf life and stability. Reconstitution allows controlled preparation for laboratory use.
• Flexible Dose Options
  The two variants allow better dose titration in different studies, helping researchers choose a lower or higher amount depending on their experimental design.

Presentation & Handling

• Form: Supplied as lyophilized peptide in sterile vial.
• Reconstitution: Use bacteriostatic water or 2% procaine; swirl gently (do not shake vigorously).
• Storage: Store at –20 °C, protected from light and moisture. After reconstitution, use according to research protocols and handle under sterile conditions.

Intended Use

For research purposes only. Must be handled in accordance with institutional protocols and ethical guidelines.