The WEIGHT·OFF Bundle integrates four complementary compounds that work through distinct yet synergistic mechanisms — controlling appetite, improving energy metabolism, and maintaining muscle tone during fat loss.

By combining a neurotransmitter reuptake inhibitor, a dual-hormonal satiety agonist, a growth hormone secretagogue, and a metabolic enzyme inhibitor, this stack provides an innovative platform for metabolic and longevity research.

🔹 Tesofensine – Triple Neurotransmitter Reuptake Inhibitor

Tesofensine acts on serotonin, norepinephrine, and dopamine pathways, three neurotransmitters responsible for appetite, motivation, and energy balance.
Research shows Tesofensine may help reduce hunger, increase energy expenditure, and enhance mood and focus during caloric restriction.
By amplifying these neurotransmitters, Tesofensine creates a neuro-metabolic environment favorable for fat reduction and performance.

🔹 Cagrilintide – Amylin Analogue for Satiety & Weight Regulation

Cagrilintide is a synthetic analogue of amylin, a hormone involved in appetite control and glucose regulation.
Studies demonstrate its ability to suppress appetite, delay gastric emptying, and support weight loss through central satiety signaling.
When combined with other metabolic peptides, Cagrilintide enhances the body’s natural ability to achieve energy balance and fat reduction.

🔹 Ipamorelin – Selective Growth Hormone Secretagogue

Ipamorelin is a highly selective GH secretagogue that increases growth hormone release without affecting cortisol or prolactin levels.
Research indicates its role in preserving lean muscle, enhancing recovery, and supporting fat metabolism, making it a valuable addition to metabolic recomposition models.

🔹 5-Amino-1MQ – NNMT Inhibitor for Metabolic Enhancement

5-Amino-1MQ is a small-molecule NNMT inhibitor that helps preserve NAD⁺ levels and improve cellular energy production.
It promotes fat oxidation, enhances insulin sensitivity, and supports muscle maintenance during weight loss.
In metabolic research, it’s recognized as a promising compound for counteracting age-related metabolic slowdown and promoting fat-to-energy conversion.

Scientific Synergy

Together, these four compounds form a research-driven system designed to:

• Reduce appetite and caloric intake

• Increase energy and metabolic output

• Preserve lean muscle during fat loss

• Improve glucose metabolism and insulin sensitivity

• Enhance motivation, focus, and satiety control

By uniting neurochemical balance with metabolic efficiency, WEIGHT·OFF represents a next-generation model for exploring body transformation and metabolic resilience at the cellular level.

Presentation & Handling

• Form: Supplied as lyophilized peptide in sterile vial.
• Reconstitution: Use bacteriostatic water (Included) or 2% procaine; swirl gently (do not shake vigorously).
• Storage: Store at –20 °C, protected from light and moisture. After reconstitution, use according to research protocols and handle under sterile conditions.
• Verify each product notes for reconstitution volumes.

Intended Use

For research purposes only. Must be handled in accordance with institutional protocols and ethical guidelines.