The WEIGHT·SUPREME Bundle integrates five powerful research compounds that act across the brain, endocrine, and cellular energy systems to deliver a multi-dimensional approach to weight management and metabolic performance.
This formula unites neurotransmitter modulation, incretin signaling, growth hormone regulation, tissue repair, and mitochondrial activation, offering researchers a full-spectrum view of human metabolism.

🔹 Tesofensine – Neurotransmitter-Based Appetite Control

Tesofensine is a triple reuptake inhibitor acting on serotonin, norepinephrine, and dopamine pathways to suppress appetite and enhance energy expenditure.
Research indicates it may help reduce caloric intake, increase motivation and focus, and enhance metabolic drive—key components for studying long-term weight regulation and behavioral metabolic control.

🔹 Tirzepatide – Dual Incretin (GIP + GLP-1) Agonist

Tirzepatide targets both GIP and GLP-1 receptors, promoting satiety, reduced appetite, and improved insulin response.
It has been shown in clinical research to deliver significant body weight reduction and metabolic improvements while maintaining lean tissue mass, making it a cornerstone peptide in advanced obesity and diabetes studies.

🔹Ipamorelin – Growth Hormone Secretagogue for Lean Mass

Ipamorelin is a selective GH secretagogue that stimulates the body’s natural release of growth hormone without increasing cortisol or prolactin.
It plays a crucial role in preserving muscle tissue, enhancing recovery, and stimulating fat metabolism, supporting studies focused on recomposition and performance.

🔹 BPC-157 – Regenerative Peptide for Tissue and Gut Health

BPC-157 promotes tissue regeneration, vascular repair, and gut protection, helping maintain cellular integrity during metabolic or caloric stress.
Its inclusion supports research into recovery, inflammation reduction, and the restoration of internal balance during weight management protocols.

🔹 SLU-PP-332 – ERR Pan-Agonist & Mitochondrial Activator

SLU-PP-332 acts as a pan-agonist of the Estrogen-Related Receptors (ERRα, β, γ)—key regulators of mitochondrial energy metabolism.
Studies describe it as an “exercise mimetic”, enhancing fat oxidation, ATP production, and metabolic flexibility, even under reduced caloric intake.
It complements the metabolic cascade initiated by the other peptides, creating a foundation for sustained energy and endurance.

Scientific Synergy

Together, these five compounds establish a research model for:

• Appetite suppression and caloric regulation

• Fat oxidation and energy expenditure

• Improved glucose utilization and insulin sensitivity

• Muscle protection and tissue repair

• Enhanced mitochondrial and metabolic function

WEIGHT·SUPREME bridges neurochemical, hormonal, and mitochondrial science—offering a holistic, research-backed pathway toward understanding total body transformation at the molecular level.

Presentation & Handling

• Form: Supplied as lyophilized peptide in sterile vial.
• Reconstitution: Use bacteriostatic water (Included) or 2% procaine; swirl gently (do not shake vigorously).
• Storage: Store at –20 °C, protected from light and moisture. After reconstitution, use according to research protocols and handle under sterile conditions.
• Verify each product notes for reconstitution volumes.

Intended Use

For research purposes only. Must be handled in accordance with institutional protocols and ethical guidelines.